Linqing Feng

Bioimage informatics, Neuroinformatics

Welcome to the Feng Lab

We develop novel image processing, computer vision, data mining and visualization algorithms to efficiently extract useful knowledge out of large-scale, heterogeneous bioimage data. We focus on developing bioimage informatics platform (e.g. neuTube ) for reconstructing and analyzing multiscale brain connectivity.

우리 연구실에서는 효율적인 뇌 이미지 및 빅데이터 처리를 위한 영상처리, Computer vision 및 데이터 마이닝 알고리즘을 개발하고 있습니다. 특히 멀티스케일 뇌신경망의 3차원 재구성 및 분석을 위한 바이오영상 정보처리 플랫폼(e.g. neuTube )을 개발하는데 주력하고 있습니다.

We are looking for passionate new Postdocs, Graduate students, and Interns to join the team! If you are interested in working with us, please send me an email. State briefly why you are interested and attach a CV.

Members

Linqing Linqing Feng, Principal Investigator

Junho 송준호 - 전문연구요원

Soomin 정수민 - Intern (Seoul National University)

Former members

Sangbin 유상빈 - 학연 (Seoul National University of Science and Technology)

Lisa Lisa Jin, Summer Intern (NSF IPAN)

Junhong Junhong Liu, Summer Intern (Zhejiang University)

Select Publications

  • Kwon, O., Feng, L., Druckmann, S., & Kim, J. (2018). Schaffer Collateral Inputs to CA1 Excitatory and Inhibitory Neurons Follow Different Connectivity Rules. Journal of Neuroscience, 38(22), 5140–5152. https://doi.org/10.1523/JNEUROSCI.0155-18.2018
  • Woo, J., Kim, J. E., Im, J. J., Lee, J., Jeong, H. S., Park, S., … Lee, C. J. (2017). Astrocytic water channel aquaporin-4 modulates brain plasticity in both mice and humans: a potential gliogenetic mechanism underlying language-associated learning. Molecular Psychiatry, 23(4), 1021–1030. https://doi.org/10.1038/mp.2017.113
  • Rah, J.-C., Feng, L., Druckmann, S., Lee, H., & Kim, J. (2015). From a meso- to micro-scale connectome: array tomography and mGRASP. Frontiers in Neuroanatomy, 9. https://doi.org/10.3389/fnana.2015.00078
  • Feng, L., Zhao, T., & Kim, J. (2015). neuTube 1.0: A New Design for Efficient Neuron Reconstruction Software Based on the SWC Format. ENeuro, 2(1). https://doi.org/10.1523/ENEURO.0049-14.2014
  • Feng, L., Kwon, O., Lee, B., Oh, W. C., & Kim, J. (2014). Using mammalian GFP reconstitution across synaptic partners (mGRASP) to map synaptic connectivity in the mouse brain. Nature Protocols, 9(10), 2425–2437. https://doi.org/10.1038/nprot.2014.166
  • Druckmann, S., Feng, L., Lee, B., Yook, C., Zhao, T., Magee, J. C., & Kim, J. (2014). Structured Synaptic Connectivity between Hippocampal Regions. Neuron, 81(3), 629–640. https://doi.org/10.1016/j.neuron.2013.11.026
  • Feng, L., Zhao, T., & Kim, J. (2012). Improved synapse detection for mGRASP-assisted brain connectivity mapping. Bioinformatics, 28(12), i25–i31. https://doi.org/10.1093/bioinformatics/bts221
  • Feng, L., Xu, Y., Yang, Y., & Zheng, X. (2011). Multiple dense particle tracking in fluorescence microscopy images based on multidimensional assignment. Journal of Structural Biology, 173(2), 219–228. https://doi.org/10.1016/j.jsb.2010.11.001